Tests based on the detection of mycobacterial lipoarabinomannan (LAM) antigen in urine have
emerged as potential point-of-care tests for tuberculosis (TB). LAM antigen is a lipopolysaccharide
present in mycobacterial cell walls, which is released from metabolically active or degenerating
bacterial cells ...
In 2004, the World Health Organization (WHO) published an interim policy on collaborative TB/HIV activities
in response to demand from countries for immediate guidance on actions to decrease the dual burden of
tuberculosis (TB) and human immunodeficiency virus (HIV). The term interim was used because the...
Earlier and improved tuberculosis (TB) case detection - including smear-negative disease, often associated with HIV co-infection - as well as expanded capacity to diagnose multidrug-resistant tuberculosis (MDR-TB) are global priorities for TB control. Conventional laboratory methods are slow and cumberso...
To improve survival and quality of life among the 2.5 million children living with HIV, a comprehensive package of prevention, care and treatment is required. This package should include management of infections such as pneumonia, diarrhoea, malaria and ear infections, as well as common opportunistic inf...
The World Health Organization (WHO) first published guidance for national
tuberculosis control programmes on managing tuberculosis in children (hereafter
called “the Guidance”) in 2006. The Guidance follows the principles of a public
health approach aimed at optimizing outcomes, including the quality...
